Prevalence of OmpK35 and OmpK36 porin expression in beta-lactamase and non-beta-lactamase-producing Klebsiella pneumoniae
نویسندگان
چکیده
منابع مشابه
Prevalence of OmpK35 and OmpK36 porin expression in beta-lactamase and non-betalactamase- producing Klebsiella pneumoniae
BACKGROUND The aims of this study were to confirm the presence of OmpK35 and OmpK36 in extended-spectrum beta-lactamase-producing and nonextended-spectrum beta-lactamase-producing Klebsiella pneumoniae and to determine the relationship between porin expression and resistance to third-generation cephalosporins. METHODS Fifty-two K. pneumoniae isolates were obtained and analyzed for extended-sp...
متن کاملAn ertapenem-resistant extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae clone carries a novel OmpK36 porin variant.
Carbapenem-resistant Klebsiella pneumoniae caused an outbreak in a hospital in Rome, Italy. The clinical isolates were tested by antimicrobial susceptibility testing, pulsed-field gel electrophoresis, multilocus sequence typing, plasmid typing, and β-lactamase identification. The OmpK35 and OmpK36 porins were analyzed by SDS-PAGE, and their genes were amplified and sequenced. Complementation ex...
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Background: Production of β–lactamases by enterobacteriacea, especially Klebsiella pneumoniae, is one of the emerging health problems in the world. The purpose of this study was to assess the frequency of blaCTX-M15 gene in K. pneumoniae isolates and determine the molecular diversity of CTXM producing isolates. Methods: In...
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BACKGROUND & AIM The aim of this study was the detection of OqxAB efflux pumps, OmpK35 and OmpK36 porins among extended-spectrum-β-lactamase-producing Klebsiella pneumoniae isolates from Iran. MATERIALS AND METHODS This study was conducted with 83 K. pneumoniae isolates from two hospitals in Tehran, Iran. Antibiotic susceptibility tests were performed by Kirby-Bauer disc diffusion and Broth M...
متن کاملRisk factors and outcome in extended spectrum beta-lactamase producing Escherichia coli and Klebsiella pneumoniae bacteremia.
Given our interest in the epidemiology of nosocomial infection, and the impact of multidrug resistance, I read with great interest the study by Dr. Memon et al1 regarding risk factors and mortality associated with bacteremia caused by extended-spectrum ß-lactamase producing (ESBL) Escherichia coli and Klebsiella pneumonia. In this study, the only variable identified as a significant risk factor...
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ژورنال
عنوان ژورنال: Biologics: Targets and Therapy
سال: 2011
ISSN: 1177-5475
DOI: 10.2147/btt.s27582